Ace the Certified Nephrology Nurse 2025 Exam – Dive into Dialysis Mastery!

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What is the definition of ultrafiltration?

Movement of small particles across a membrane

Filtration using a medium retaining large molecules

Ultrafiltration is defined as the process in which a liquid is filtered through a membrane that selectively retains larger molecules while allowing smaller particles, such as water and solutes, to pass through. This filtration mechanism is essential in various clinical settings, particularly in nephrology, where it helps in the removal of excess fluids and waste from the body while preserving essential proteins and cells in the bloodstream.

In the context of nephrology, ultrafiltration is a crucial principle applied in renal replacement therapies, such as dialysis. It operates by creating a pressure gradient that facilitates the movement of water and small solutes across a semipermeable membrane while preventing the loss of larger molecules, which are vital for physiological functions.

Other choices do not accurately capture this process. For instance, the movement of small particles across a membrane is more indicative of basic filtration rather than specifically ultrafiltration, which emphasizes the selective retention of larger molecules. Evaporation of fluid from the body refers to a phase change of matter rather than filtration and is not a relevant description of ultrafiltration. Lastly, absorption of water through a semipermeable membrane suggests a different mechanism, such as osmosis, where water moves from an area of lower solute concentration to one of higher concentration

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Evaporation of fluid from the body

Absorption of water through a semipermeable membrane

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